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Liver microsomes provide a readily available and well-characterized biological model for use in CYP enzyme inhibition studies. InVitroCYP H-class microsomes are prepared from tissues that are screened and selected for high activity across the panel of relevant cytochrome P450 enzymes, including those CYPs that are traditionally low in activity. This microsome classification provides researchers with enhanced sensitivity on typically low activity CYPs.
Product No. |
Description |
X008061 |
InVitroCYP H-class 10-Donor Pooled Human Liver Microsomes, 10 mg |
X008062 |
InVitroCYP H-class 10-Donor Pooled Human Liver Microsomes, 20 mg |
X008063 |
InVitroCYP H-class 10-Donor Pooled Human Liver Microsomes, 100 mg |
X008064 |
InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 10 mg |
X008065 |
InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 20 mg |
X008066 |
InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 100 mg |
FX008061 |
InVitroCYP H-class 10-Donor Female Pooled Human Liver Microsomes, 10 mg |
FX008062 |
InVitroCYP H-class 10-Donor Female Pooled Human Liver Microsomes, 20 mg |
MX008061 |
InVitroCYP H-class 10-Donor Male Pooled Human Liver Microsomes, 10 mg |
MX008062 |
InVitroCYP H-class 10-Donor Male Pooled Human Liver Microsomes, 20 mg |
FX008064 |
InVitroCYP H-class 25-Donor Female Pooled Human Liver Microsomes, 10 mg |
FX008065 |
InVitroCYP H-class 25-Donor Female Pooled Human Liver Microsomes, 20 mg |
MX008064 |
InVitroCYP H-class 25-Donor Male Pooled Human Liver Microsomes, 10 mg |
MX008065 |
InVitroCYP H-class 25-Donor Male Pooled Human Liver Microsomes, 20 mg |
F008084 |
InVitroCYP H-class Individual Female Human Liver Microsomes, 10 mg |
F008085 |
InVitroCYP H-class Individual Female Human Liver Microsomes, 20 mg |
M008084 |
InVitroCYP H-class Individual Male Human Liver Microsomes, 10 mg |
M008085 |
InVitroCYP H-class Individual Male Human Liver Microsomes, 20 mg |
Features and Benefits
- Pooled. Purpose-pooledSM using a proprietary alogorithm to achieve targeted high enzyme levels.
- Quality. Celsis IVT microsomes are quality checked by our independent quality control and quality assurance lab to guarantee quality and consistency
- Characterization. Celsis’ extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP microsomes will provide consistent and reproducible results.
- Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes across experiments.
- Choice. Available in 10-, 20-, and 100-mg sizes.
The protein concentrations listed in the following tables are approximate. Please check the product data sheet for lot-specific protein content. InVitroCYP human liver microsomes are sold in vials of 0.5 mL (10 mg), 1 mL (20 mg), and 5 mL (100 mg). Characterization information is available online at www.celsis.com/characterisation.html.
Storage
InVitroCYP human liver microsomes must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.
Stability
Historical data demonstrates that when stored under the recommended conditions, our human liver microsomes are stable for five (5) years. Celsis IVT is continually performing stability studies, following ICH guidelines, to validate and extend product shelf life.
Product Information
Technical Sheet for InVitroCYP H-class
InVitroCYP Product Literature
InVitroCYP Characterization Tables
Related Products
InVitroCYP M-class
InVitroCYP C-class
Animal Microsomes
For questions about Celsis In Vitro Technologies InVitroCYP Microsomes, contact Customer Service at (888) 488-3232 or send an e-mail message to IVTcustomerservice@celsis.com.
Caution:
This product was prepared from fresh human tissue. Treat all products containing human-derived materials as potentially infectious, as no known test methods can offer assurance that products derived from human tissues will not transmit infectious agents.
These products are for research use only. Do not use in animals or humans. These products have not been approved for any diagnostic or clinical procedures.
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