InVitroCYP™ M-class™ Microsomes
Human liver microsomes are subcellular fractions that contain drug-metabolizing enzymes including CYP enzymes, flavin monooxygenases, and UDP glucuronyl transferases.  InVitroCYP M-class microsomes are designed to exhibit moderate CYP activity, ideal for clearance and metabolite identification studies. Celsis’ extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP M-class microsomes will provide consistent and reproducible results for your metabolism and clearance studies.

Features and Benefits

• Pooled. Purpose-pooledSM using a proprietary alogorithm to achieve targeted average enzyme levels.
• Quality. Celsis IVT microsomes are quality checked by our independent quality control and quality assurance lab to guarantee quality and consistency
• Characterization. Celsis’ extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP microsomes will provide consistent and reproducible results.
• Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes across experiments.
• Choice. Available in 10-, 20-, and 100-mg sizes.

The protein concentrations listed in the following tables are approximate.  Please check the product data sheet for lot-specific protein content.  InVitroCYP human liver microsomes are sold in vials of 0.5 mL (10 mg), 1 mL (20 mg), and 5 mL (100 mg).  Characterization information is available online at www.celsis.com/characterisation.html.

Storage
InVitroCYP human liver microsomes must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.

Stability
Historical data demonstrates that when stored under the recommended conditions, our human liver microsomes are stable for five (5) years. Celsis IVT is continually performing stability studies, following ICH guidelines, to validate and extend product shelf life.

Product Information
Technical Sheet for InVitroCYP M-class
InVitroCYP Product Literature
InVitroCYP Characterization Tables

Related Products
InVitroCYP H-class
InVitroCYP C-class
Animal Microsomes

For questions about Celsis In Vitro Technologies InVitroCYP Microsomes, contact Customer Service at (888) 488-3232 or fill out this form today.

Caution:
This product was prepared from fresh human tissue. Treat all products containing human-derived materials as potentially infectious, as no known test methods can offer assurance that products derived from human tissues will not transmit infectious agents.

These products are for research use only. Do not use in animals or humans. These products have not been approved for any diagnostic or clinical procedures.