Animal Microsomes & S9

Microsomes are a valuable tool for studying the metabolism of your compounds and for examining potential drug-drug interactions. Celsis IVT prepares animal liver microsomes and S9 fractions from a variety of species, including:

• Mouse (ICR/CD-1)
• Rat (Sprague-Dawley, Wistar, and Fischer 344)
• Guinea pig (Dunkin-Hartley)
• Dog (Beagle)
• Rabbit (New Zealand White)
• Minipig (Yucatan)
• Monkey (Cynomolgus and Rhesus)

In addition to pooled microsome and S9 produced from control laboratory animals, we offer fully characterized, pooled microsomes and S9 from Sprague-Dawley® rat tissue that has been treated with different chemical enzyme inducers, including the following:

• Aroclor 1254
• b-Naphthoflavone
• Clofibrate
• Dexamethasone
• Isoniazid
• 3-Methylcholanthrene
• Phenobarbital

Celsis IVT can prepare custom orders of microsomes, S9 and hepatocytes from other species not found on this list. Custom sizes are also available. Learn more about our custom products.  For a custom product quote, please complete our custom product form.

Features and Benefits

• Quality. Celsis IVT microsomes and S9 are quality checked by our independent quality control and quality assurance lab to guarantee quality and consistency.
• Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes and S9 across experiments.

For questions about our products, contact Celsis IVT or call Customer Service at  (888) 488-3232 

Storage
Animal liver microsomes and S9 must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.

Industry Caution